Search results for "Metabolic Stress"
showing 3 items of 3 documents
Fermentation at non-conventional conditions in food- and bio-sciences by the application of advanced processing technologies
2017
The interest in improving the yield and productivity values of relevant microbial fermentations is an increasingly important issue for the scientific community. Therefore, several strategies have been tested for the stimulation of microbial growth and manipulation of their metabolic behavior. One promising approach involves the performance of fermentative processes during non-conventional conditions, which includes high pressure (HP), electric fields (EF) and ultrasound (US). These advanced technologies are usually applied for microbial inactivation in the context of food processing. However, the approach described in this study focuses on the use of these technologies at sub-lethal levels,…
DNA Photodamage and Repair: Computational Photobiology in Action
2020
DNA is constantly exposed to external and metabolic stress agents, including the solar radiation and in particular the UV portion of the electromagnetic spectrum. Such source of stress can induce photochemical modification of the structure of DNA and of its basic components, i.e. the nucleobases. DNA lesions may ultimately lead to genomic instability, mutations, and even to carcinogenesis. Hence, cells dispose of complex biochemical repair pathways in charge of remove the DNA lesions and avoid their accumulation. In this Chapter, we present the complexity of the DNA lesion chemical and structural space, also complicated by the intricate coupling with the biological relevant signaling pathwa…
Dental disease in a 17th–18th century German community in Jelgava, Latvia
2012
Aims: To determine the frequency and distribution of dental caries, periapical lesions, the periodontal disease, ante-mortem tooth loss and enamel hypoplasia in a high status, urban post-medieval population from the Duchy of Courland and Semigallia, and to compare these rates with those obtained from contemporary populations from urban and rural Latvian cemeteries. Materials: The sample analysed consisted of the dental remains of 108 individuals (39 male, 42 female and 27 non-adults) excavated from the Jelgava Holy Trinity Church cemetery in Latvia. A total of 1,233 teeth and 1,853 alveoli were examined. Results: The frequency of the observed conditions in this population was overall high b…